Entrepreneurship

An Interesting Startup

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Here’s a company, Hadrian, which is planning to build a series of factories for manufacturing of precision metal components.   Their first factory is in Hawthorne, CA, and they’re building the next one nearby in Torrance.

One of the lead investors in Hadrian is the VC firm Andreessen Horowitz.   The A-H partner responsible for this deal, Katherine Boyle, writes about the company, the opportunity, and why she considers it a promising investment.

Hadrian is hiring, if anyone’s interested.

Also, a thoughtful piece from Ms Boyle on the need for America to get serious.

Alternative Structure

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I did note this story on Axios, which was discussed scathingly and at length on Ace of Spades; that the Lefty Progs have belatedly realized that, yes indeedy, us social and political conservatives are building our alternate establishments, in media, money-management, retail, and everywhere else. Welcome to the party, pal… It goes without saying that the Lefty Progs disapprove, most indignantly. I noted the split a little more than a year ago, in this post.

We’re already at the split. We read different books, watch different movies and television shows those of us who still watch movies and television follow different celebrities, earn a living in different ways, educate our children differently. We honor different things, different heroes and heroines, have wildly different aspirations and hopes for the future. We are already split.

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The Erector Set

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Here is an old post from my own blog. I thought it deserved another go.

Glenn Reynolds today has a link to Lionel Trains in the anticipation of Christmas. I had Lionel trains and eventually had HO gauge trains, as well. When I had sons old enough to play with trains, I built an elaborate train set in my garage. Then I learned that southern California is not the place for toy trains. The boys were outdoors all the time and the train set gathered dust.

Another toy that kids today will never have the chance to enjoy is the Erector Set. There is still a small source for this toy but the glory days of the Erector Set were long ago. The toy was invented by A.C. Gilbert in 1913. The story is interesting. Gilbert was a Yale Medical School graduate and had also won a gold medal, for the pole vault, in the 1908 Olympic Games. He had a new design bamboo pole that he used in his winning vault and he sold these, as well as other toys.

Like many residents of New Haven, Connecticut, he often took the train to New York City; and on one trip in 1911 he was inspired with what would be the most popular of his dozens of inventions.

Watching out the train window as some workmen positioned and riveted the steel beams of an electrical power-line tower, Gilbert decided to create a children’s construction kit: not just a toy, but an assemblage of metal beams with evenly spaced holes for bolts to pass through, screws, bolts, pulleys, gears and eventually even engines. A British toy company called Meccano Company was then selling a similar kit, but Gilbert’s Erector set was more realistic and had a number of technical advantages — most notably, steel beams that were not flat but bent lengthwise at a 90-degree angle, so that four of them nested side-to-side formed a very sturdy, square, hollow support beam.

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Reason #564 To Be Glad …

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…That I am my own independent publisher, with the Tiny Publishing Bidness, and only wasted a couple of months and a lot of postage, in 2007 or so, trying to get an agent interested in my first two novels. Because that was the way to break into traditional publishing; get an agent, who would present your work to the traditional publishing houses. Another book blogger at the time advised trying it for a year, and then going independent, as there were sufficient small companies doing publish-on-demand, some of them for rather reasonable fees. I did have an interested agent in New York, who was referred to me by another milblogger back then, and although the agent reluctantly declined to offer me his services, he was jolly complimentary and encouraging, and provided some good insights. One of the unspoken insights that I took away from this exchange, and drew from all the other letters saying “Thanks, but no thanks” from various literary agencies was that it was all a terribly insular world, the world of the established agencies and big publishers, all of whom seemed to be based in about half a square mile of real estate in New York.

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SARS-CoV2/COVID-19 Update, Easter 2020 edition

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There are lots of hopeful reports — despite the USA COVID-19 infections being over 1/2 million and the total deaths of over 20,000 people — that the pandemic will soon be “Over.”

This is fantasy thinking at best.   SARS-CoV2/COVID-19  won’t be over, until it is over, for YEARS.

“Over” being defined as world wide mass vaccinations to the tune of 70% of humanity or human herd immunity.   Assuming such a thing is possible, which it may not be, given this recent report from the UK Daily Mail on post SARS-CoV2/COVID-19 infection immunity —

Blow to Britain’s hopes for coronavirus antibody testing as study finds a THIRD of recovered patients have barely-detectable evidence they have had the virus already

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– Nearly third of patients have very low levels of antibodies, Chinese study found
– Antibodies not detected at all in 10 people, raising fears they could be reinfected
– Explains why UK Government repeatedly delayed rolling them out to the public

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https://www.dailymail.co.uk/news/article-8203725/Antibodies-prove-difficult-detect-Chinese-coronavirus-survivors.html

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Related studies:
Wu F et al. Neutralizing antibody responses to SARS-CoV-2 in a COVID-19 recovered patient cohort and their implications. medRxiv 2020.03.30.20047365; doi: https://doi.org/10.1101/2020.03.30.20047365

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and

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Zhao J et al. Antibody responses to SARS-CoV-2 in patients of novel coronavirus disease 2019, Clinical Infectious Diseases, , ciaa344, https://doi.org/10.1093/cid/ciaa344
total by July 1st 51,197

Or this  South Korean story on coronavirus “reactivation” —

South Korea reports recovered coronavirus patients testing positive again
APRIL 10, 2020
Josh Smith, Sangmi Cha

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https://www.reuters.com/article/us-health-coronavirus-southkorea-idUSKCN21S15X?utm_campaign=trueAnthem%3A+Trending+Content&utm_medium=trueAnthem&utm_source=facebook

The issue with most COVID-19 tests, like the ones mentioned in South Korea, is they detect SARS-CoV2 RNA. They do not detect whether the viral particles are active or not. The issue here is whether these people are shedding active viral particles that can re-infect people.    We don’t know if that is the case here from the story text.   Given how infectious it is.   This coronavirus will tell us in due course.

There are some viral diseases like Herpes that hide inside your body and reactivate to make you infectious. We do not know enough about the SARs-CoV2 virus to say whether that is the case here.

If the SARS-CoV2 virus is like Herpes in that once contracted, it never goes away and flares infectious several times a year.

And there is no herd immunity for some people no matter how often they are infected.

Then we will need multiple, cheap,   out-patient style “cure-treatments” as well as multiple vaccines, based on co-morbidities, and possibly to account for racial differences like sickle cell blood mutations, as SARS-CoV2 may well be more a blood disease than a respiratory infection in terms of it’s killing mechanism.

See:

COVID-19: Attacks the 1-Beta Chain of Hemoglobin and Captures the Porphyrin to Inhibit Human Heme Metabolism

https://chemrxiv.org/articles/COVID-19_Disease_ORF8_and_Surface_Glycoprotein_Inhibit_Heme_Metabolism_by_Binding_to_Porphyrin/11938173

There is not enough reliable data, d*mn it!

Until we get to “Over,” our old economic world of Just-In-Time, Sole Source anywhere, but especially in China, is dead without replacement.

The world is in the same position as Germany was from August 1944 – April 1945 or   Japan from August 1944 until August 1945 versus the Allied strategic bombing campaign.   We have entered the world of   “End Run Production“ as world wide supply chains grind to a halt from various fiddly bits of intermediate parts running out without replacement.   The on-and-off hotspots world wide of COVID-19 at different times and places in the world economy is no different than WW2 strategic bombing in terms of causing random damage to the economic life support.

See also   “End Run Production” here from this one volume WW2 history book The Great Crusade:

https://books.google.com/books?id=5L-bwPZK7PQC&pg=PA420&lpg=PA420&dq=%22End+Run+Production%22&source=bl&ots=kc30FQflCj&sig=ACfU3U2kmF-kTPo0Tgr2A9_ESPKpEQAEOg&hl=en&sa=X&ved=2ahUKEwjfpurOnOPoAhUKA6wKHemwBMcQ6AEwAHoECC4QKQ#v=onepage&q=%22End%20Run%20Production%22&f=false

Be it automobiles, self propelled construction equipment, jets, power plants or the latest electronic gadget, anything that has thousands of parts sourced world wide with lots of Chinese cheap/disposable sub-component content anywhere in the supply chain simply won’t be produced for the next 18 months to three years.

This “random damage to the economic life support” effect is amplified by the unwillingness of Western private industry to invest in building the capitol equipment to produced those intermediate parts.   Because of the threat of China coming back with predatory pricing — using bought politicians to cover for them — means those parts won’t be built without massive cost plus contract government buy out of the investment risk like happened in the USA in the 1942 WW2 mobilization.

The story of   one American n95 mask manufacturer’s experience with the Obama Administration in 2009 with the Swine flu is a case in point.   The n95 mask is a 50 cent item where China pays 2 cents a mask for labor versus 10 cents a mask for American labor.   When the American manufacturer geared up to replace Chinese mask production.   China came back on-line and the Obama Administration refused to keep buying the American mask producer’s 8 cents more expensive mask when the Chinese masks were available.

Unlike almost 80 years ago, current Western and particularly American politicians are too corrupt to go too massive cost plus contract government buy out this private investment risk.   Mainly because these political elites   can’t be bothered to figure out their 10% cut.   Instead we are getting more “fiscal stimulus” AKA boondoggles that the elites will saddle the rest of us with high interest payments on huge public debts.

It will take local small to mid-sized business to get the American economy going during the COVID-19 pandemic via making products and services that don’t use the intermediate products China threatens with when the pandemic ends.

My read on what comes next economically is local/distributed production with limited capitol investment that is multi-product capable.   The name for that is additive manufacturing, AKA 3D Printing. Here are a couple of examples:

  1. The idea of 3D  Printed Sand Casting Molds For Automobile Production

voxeljet enters alliance to industrialize core tooling production using 3D printing

2. And the replacement of physical inventory with 3D printers, print media and electronic drawings:
Such “Make or buy” decisions have always been the key decision of any business.   The issue here is that middle men wholesalers and in-house warehousing holding cheap Chinese-sourced   intermediate parts are both set to go the way of the Doe-Doe Bird in a 3D/AM manufacturing dominated world.
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Distributed production in multiple localities with 3D/AM vendors for limited runs of existing intermediate products to keep production lines going.   Or the re-engineering intermediate products so one 3D/AM print replaces multiple intermediate products for the same reason, will be the stuff of future Masters of Business Administration (MBA) papers describing this imminent change over.

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But, like developing SARS-CoV2/COVID-19 vaccines, this new locally distributed manufacturing economy will take time.   The possible opening of the American economy in May 2020 will not bring the old economy of December 2019 back.

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That economy is dead.   It cannot, will not, come back.

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We will have to dance with both the sickness from SARS-CoV2/COVID-19 and the widening “End Run Production“ product shortages that the death of the globalist   just-in-time, sole source in China economic model causes for years.

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And this is a hard reality, not a fantasy, we must all face.