SARS-CoV2/COVID-19 Update, Easter 2020 edition

There are lots of hopeful reports — despite the USA COVID-19 infections being over 1/2 million and the total deaths of over 20,000 people — that the pandemic will soon be “Over.”

This is fantasy thinking at best.   SARS-CoV2/COVID-19  won’t be over, until it is over, for YEARS.

“Over” being defined as world wide mass vaccinations to the tune of 70% of humanity or human herd immunity.   Assuming such a thing is possible, which it may not be, given this recent report from the UK Daily Mail on post SARS-CoV2/COVID-19 infection immunity —

Blow to Britain’s hopes for coronavirus antibody testing as study finds a THIRD of recovered patients have barely-detectable evidence they have had the virus already

.

– Nearly third of patients have very low levels of antibodies, Chinese study found
– Antibodies not detected at all in 10 people, raising fears they could be reinfected
– Explains why UK Government repeatedly delayed rolling them out to the public

.

https://www.dailymail.co.uk/news/article-8203725/Antibodies-prove-difficult-detect-Chinese-coronavirus-survivors.html

.

Related studies:
Wu F et al. Neutralizing antibody responses to SARS-CoV-2 in a COVID-19 recovered patient cohort and their implications. medRxiv 2020.03.30.20047365; doi: https://doi.org/10.1101/2020.03.30.20047365

.

and

.

Zhao J et al. Antibody responses to SARS-CoV-2 in patients of novel coronavirus disease 2019, Clinical Infectious Diseases, , ciaa344, https://doi.org/10.1093/cid/ciaa344
total by July 1st 51,197

Or this  South Korean story on coronavirus “reactivation” —

South Korea reports recovered coronavirus patients testing positive again
APRIL 10, 2020
Josh Smith, Sangmi Cha

.

https://www.reuters.com/article/us-health-coronavirus-southkorea-idUSKCN21S15X?utm_campaign=trueAnthem%3A+Trending+Content&utm_medium=trueAnthem&utm_source=facebook

The issue with most COVID-19 tests, like the ones mentioned in South Korea, is they detect SARS-CoV2 RNA. They do not detect whether the viral particles are active or not. The issue here is whether these people are shedding active viral particles that can re-infect people.    We don’t know if that is the case here from the story text.   Given how infectious it is.   This coronavirus will tell us in due course.

There are some viral diseases like Herpes that hide inside your body and reactivate to make you infectious. We do not know enough about the SARs-CoV2 virus to say whether that is the case here.

If the SARS-CoV2 virus is like Herpes in that once contracted, it never goes away and flares infectious several times a year.

And there is no herd immunity for some people no matter how often they are infected.

Then we will need multiple, cheap,   out-patient style “cure-treatments” as well as multiple vaccines, based on co-morbidities, and possibly to account for racial differences like sickle cell blood mutations, as SARS-CoV2 may well be more a blood disease than a respiratory infection in terms of it’s killing mechanism.

See:

COVID-19: Attacks the 1-Beta Chain of Hemoglobin and Captures the Porphyrin to Inhibit Human Heme Metabolism

https://chemrxiv.org/articles/COVID-19_Disease_ORF8_and_Surface_Glycoprotein_Inhibit_Heme_Metabolism_by_Binding_to_Porphyrin/11938173

There is not enough reliable data, d*mn it!

Until we get to “Over,” our old economic world of Just-In-Time, Sole Source anywhere, but especially in China, is dead without replacement.

The world is in the same position as Germany was from August 1944 – April 1945 or   Japan from August 1944 until August 1945 versus the Allied strategic bombing campaign.   We have entered the world of   End Run Production as world wide supply chains grind to a halt from various fiddly bits of intermediate parts running out without replacement.   The on-and-off hotspots world wide of COVID-19 at different times and places in the world economy is no different than WW2 strategic bombing in terms of causing random damage to the economic life support.

See also   “End Run Production” here from this one volume WW2 history book The Great Crusade:

https://books.google.com/books?id=5L-bwPZK7PQC&pg=PA420&lpg=PA420&dq=%22End+Run+Production%22&source=bl&ots=kc30FQflCj&sig=ACfU3U2kmF-kTPo0Tgr2A9_ESPKpEQAEOg&hl=en&sa=X&ved=2ahUKEwjfpurOnOPoAhUKA6wKHemwBMcQ6AEwAHoECC4QKQ#v=onepage&q=%22End%20Run%20Production%22&f=false

Be it automobiles, self propelled construction equipment, jets, power plants or the latest electronic gadget, anything that has thousands of parts sourced world wide with lots of Chinese cheap/disposable sub-component content anywhere in the supply chain simply won’t be produced for the next 18 months to three years.

This “random damage to the economic life support” effect is amplified by the unwillingness of Western private industry to invest in building the capitol equipment to produced those intermediate parts.   Because of the threat of China coming back with predatory pricing — using bought politicians to cover for them — means those parts won’t be built without massive cost plus contract government buy out of the investment risk like happened in the USA in the 1942 WW2 mobilization.

The story of   one American n95 mask manufacturer’s experience with the Obama Administration in 2009 with the Swine flu is a case in point.   The n95 mask is a 50 cent item where China pays 2 cents a mask for labor versus 10 cents a mask for American labor.   When the American manufacturer geared up to replace Chinese mask production.   China came back on-line and the Obama Administration refused to keep buying the American mask producer’s 8 cents more expensive mask when the Chinese masks were available.

Unlike almost 80 years ago, current Western and particularly American politicians are too corrupt to go too massive cost plus contract government buy out this private investment risk.   Mainly because these political elites   can’t be bothered to figure out their 10% cut.   Instead we are getting more “fiscal stimulus” AKA boondoggles that the elites will saddle the rest of us with high interest payments on huge public debts.

It will take local small to mid-sized business to get the American economy going during the COVID-19 pandemic via making products and services that don’t use the intermediate products China threatens with when the pandemic ends.

My read on what comes next economically is local/distributed production with limited capitol investment that is multi-product capable.   The name for that is additive manufacturing, AKA 3D Printing. Here are a couple of examples:

  1. The idea of 3D  Printed Sand Casting Molds For Automobile Production

voxeljet enters alliance to industrialize core tooling production using 3D printing

2. And the replacement of physical inventory with 3D printers, print media and electronic drawings:
Such “Make or buy” decisions have always been the key decision of any business.   The issue here is that middle men wholesalers and in-house warehousing holding cheap Chinese-sourced   intermediate parts are both set to go the way of the Doe-Doe Bird in a 3D/AM manufacturing dominated world.
.
Distributed production in multiple localities with 3D/AM vendors for limited runs of existing intermediate products to keep production lines going.   Or the re-engineering intermediate products so one 3D/AM print replaces multiple intermediate products for the same reason, will be the stuff of future Masters of Business Administration (MBA) papers describing this imminent change over.

.

But, like developing SARS-CoV2/COVID-19 vaccines, this new locally distributed manufacturing economy will take time.   The possible opening of the American economy in May 2020 will not bring the old economy of December 2019 back.

.

That economy is dead.   It cannot, will not, come back.

.

We will have to dance with both the sickness from SARS-CoV2/COVID-19 and the widening End Run Production product shortages that the death of the globalist   just-in-time, sole source in China economic model causes for years.

.

And this is a hard reality, not a fantasy, we must all face.

The Beginning of the Okinawa Campaign — Plus 75 years

In the press of events related to the Great Wuhan Coronavirus Pandemic, many anniversaries of the Second World War have been passing by with little notice and less comment.   For example, April 1st 2020 was the 75th Anniversary of the April   1st 1945 “Love-Day” landings on the western shores of Okinawa.

This is the West Point Atlas map of the 1 April 1945 Love Day landings through 8 April 1945.
Figure 1 – This is the West Point Atlas map of both the 1 April 1945 Love Day landings through 8 April 1945 and initial Imperial Japanese 32nd Army dispositions to defend Okinawa.

The Okinawa campaign in WW2 has often been described as marking the end old style total war. Where “cork screw and blow torch” close combat to the death between American attackers “who fought to live” and Japanese defenders who “died in order to fight” played out its last dance.

This is a photo of the USMC III Corps Landing beachhead on Okinawa a April 1945.
Figure 2 – This is a photo of the USMC III Corps Landing beachhead on Okinawa April 1, 1945.

Upon closer examination, as this 75th anniversary article series will demonstrate, Okinawa is far better described as a high tech war for the electromagnetic spectrum between technological peer competitors air and naval forces.   A “secret radar war,” if you will, where two opposing command, control, communications and intelligence (C3I) sensor networks were directing land, sea and air forces in a series of both combat and logistical moves and countermoves.

And while the less advanced, and organizationally deficient, Japanese military lost Okinawa proper. It still took advantage of the primarily US Navy institutional biases, American military inter-service rivalries, logistical planning weaknesses caused by that rivalry and US Navy’s unwillingness to learn from “non-approved” sources to never the less defeat the US Navy’s original Phase III plan to overrun the upper Ryukyu’s and install island air and radar bases close enough Kyushu to properly provide land based air superiority for the invasion of Japan.

These campaign objective failures were hidden in tales of US Navy destroyer picket heroism in the “Fleet That Came to Stay:…and classified top secret files…because of the coming budget war associated with the pending merger of the War and Navy department’s into the Department of Defense.   After 75 years, this series will part the curtains on these hidden histories.

 

This is a map of the Ryukyu Island chain with Okinawa at the lower center-right. It's location would allow American airpower to dominate the sea lanes from China and Korea to Japan. Phase III of Operation Iceberg was to capture Miyako Jima for the RAF Bomber Command Tiger Force as well as Kikaiga Jima, Amami Oshima and Tokuno Shima for fighter bases to cover the Operation Olympic landings on Kyushu.
figure 3 – This is a map of the Ryukyu Island chain with Okinawa at the lower center-right. It’s location would allow American airpower to dominate the sea lanes from China and Korea to Japan. Phase III of Operation Iceberg was to capture Miyako Jima at the lower center-left for the RAF Bomber Command Tiger Force as well as Kikaiga Jima, Amami Oshima and Tokuno Shima for USAAF & USMC fighter bases to cover the planned Operation Olympic landings on Kyushu.

Too accomplish that objective, this series will examine the planned goals of the Operation Iceberg campaign against what was accomplished. How various American military institutions, doctrine and planning failed.   And why the defeat of the US Navy’s   Phase III plans set the stage for an American blood bath of preventable naval casualties during the planned Operation Olympic assault of the Japanese home islands, had the atomic bombings of Hiroshima and Nagasaki not made the invasion of Japan unnecessary.

The yellow highlighted names on this map show island in the Ryukyu chain that hosted Japanese air bases that were used through out the 83 day Okinawa campaign as staging areas for kamikaze, spotter and snooper aircraft. These bases were never fully suppressed by American or British air strikes.
Figure 4 – The yellow highlighted names on this map show islands in the Ryukyu chain that hosted Japanese air bases that were used through out the 83 day Okinawa campaign as staging areas for kamikaze, visual spotter and radar snooper aircraft. These bases were never fully suppressed by American or British carrier air strikes. Three of these air bases were scheduled for invasion and capture in the Operation Iceberg Phase III plans. None of these bases were taken due to US Navy casualties from the fanatical Japanese resistance on and around Okinawa.

Read more

Texas Aggie Doctor Reports — Clinical Pearls Covid 19 for ER practitioners

The following information is from a front line ER doctor using the handle of ‘nawlinsag’ on a Texas Aggie web site.   I’ve included the link below.  I’ve also included the complete text of his post in full in hopes medical professionals and lay people could get the most benefit from his observations of the course of COVID-19 in a small front line Louisiana hospital.

Short form: This is not the flu.   It is a horror show of death and disablement that is crowding out all other medical care including an immediate downgrade of life saving cardiac care.   Only on in seven people put on ventalators in this hospital is surviving, and then only after 10-t0-12 days of ventalator support.

—–

https://texags.com/forums/84/topics/3102444?fbclid=IwAR3s13SRnw7YNgtu-7LZyrMUSMIRRWScU67lwbuwZM8fna-6R8k4tqrtO3w

I just spent an hour typing a long post that erased when I went to change the title so I apologize to the grammar and spelling police. This one will not be proofread and much shorter.

I am an ER MD in New Orleans. Class of 98. Every one of my colleagues have now seen several hundred Covid 19 patients and this is what I think I know.

Clinical course  is predictable.
2-11 days after exposure (day 5 on average) flu like symptoms start. Common are fever, headache, dry cough, myalgias(back pain), nausea without vomiting, abdominal discomfort with some diarrhea, loss of smell, anorexia, fatigue.

Day 5 of symptoms- increased SOB, and bilateral viral pneumonia from direct viral damage to lung parenchyma.

Day 10- Cytokine storm leading to acute ARDS and multiorgan failure. You can literally watch it happen in a matter of hours.

81% mild symptoms, 14% severe symptoms requiring hospitalization, 5% critical.

Patient presentation is varied. Patients are coming in hypoxic (even 75%) without dyspnea. I have seen Covid patients present with encephalopathy, renal failure from dehydration, DKA. I have seen the bilateral interstitial pneumonia on the xray of the asymptomatic shoulder dislocation or on the CT’s of the (respiratory) asymptomatic polytrauma patient. Essentially if they are in my ER, they have it. Seen three positive flu swabs in 2 weeks and all three had Covid 19 as well. Somehow this ***** has told all other disease processes to get out of town.

China reported 15% cardiac involvement. I have seen covid 19 patients present with myocarditis, pericarditis, new onset CHF and new onset atrial fibrillation. I still order a troponin, but no cardiologist will treat no matter what the number in a suspected Covid 19 patient. Even our non covid 19 STEMIs at all of our facilities are getting TPA in the ED and rescue PCI at 60 minutes only if TPA fails.

Diagnostic
CXR- bilateral interstitial pneumonia (anecdotally starts most often in the RLL so bilateral on CXR is not required). The hypoxia does not correlate with the CXR findings. Their lungs do not sound bad. Keep your stethoscope in your pocket and evaluate with your eyes and pulse ox.

Labs- WBC low, Lymphocytes low, platelets lower then their normal, Procalcitonin normal in 95%
CRP and Ferritin elevated most often. CPK, D-Dimer, LDH, Alk Phos/AST/ALT commonly elevated.
Notice D-Dimer- I would be very careful about CT PE these patients for their hypoxia. The patients receiving IV contrast are going into renal failure and on the vent sooner.

Basically, if you have a bilateral pneumonia with normal to low WBC, lymphopenia, normal procalcitonin, elevated CRP and ferritin- you have covid-19 and do not need a nasal swab to tell you that.

A ratio of absolute neutrophil count to absolute lymphocyte count greater than 3.5 may be the highest predictor of poor outcome. the UK is automatically intubating these patients for expected outcomes regardless of their clinical presentation.

An elevated Interleukin-6 (IL6) is an indicator of their cytokine storm. If this is elevated watch these patients closely with both eyes.

Other factors that appear to be predictive of poor outcomes are thrombocytopenia and LFTs 5x upper limit of normal.

Read more

SARS-CoV2/COVID-10 Update 3-5-2020 — “As long as you remember to keep breathing and don’t fall asleep, it’s basically just like the flu.”

Issues covered will be on COVID-19 spread, World Headlines, the 3-4-2020 Seattle Public Health Press conference, World Headlind Summary,  Corruption at the WHO, Bad and good news COVID-19 medical developments. the Political/Demographic Implications of COVID-19 for the Gov’t  Elites, and the social media and videos COVID-19 tracking source section.

Top line, There are currently 97,138 confirmed COVID-19 cases worldwide, including 3,351 fatalities as of the March 5, 2020, at he 4:48pm ET time hack on the BNO News corona virus tracking site (https://bnonews.com/index.php/2020/02/the-latest-coronavirus-cases/) There are 80(+) and growing umber of nations including China plus three “Chinese special administrative regions” (Macao, Hong Kong and Taiwan) that have reported COVID-19 infections. China, Taiwan, Hong Kong, Japan, Thailand, Singapore, Italy, Iran, Germany, R.O.K. and the USA all appear to have local, or endemic, spread of the disease. Russia, Egypt, and Columbia appear to have joined the endemic spread list as well due to airports in the UAE and elsewhere picking up air travelers originating from those nations as sick with COVID-19.

WORLD HEADLINE SUMMARY (3/5/2020)

o New Jersey confirms first presumptive case
o NY state cases double to 22
o Seattle closes 26 schools
o Pentagon tracking 12 possible COVID-19 cases
o Illinois reports 5 more cases
o NYC reports 2 more cases, raising total to 4
o Italy postpones referendum vote; death toll hits 148
o WHO’s Tedros: “Now’s the time to pull out the stops”
o Tennessee confirms case
o Nevada confirms first case
o New Delhi closes primary schools
o EU officials weigh pushing retired health-care workers back into service to combat virus
o Italy to ask EU for permission to raise budget deficit as lawmakers approve €7.5 billion euros
o Beijing tells residents not to share food
o 30-year-old Chinese man dies in Wuhan 5 days after hospital discharge
o Cali authorities tell ‘Grand Princess’ cruise ship not to return to port until everyone is tested
o Global case total passes 95k
o Lebanon sees cases double to 31
o France deaths climb to 7, cases up 138 to 423
o EY sends 1,500 Madrid employees home after staffer catches virus
o Trump says he has a “hunch” true virus mortality rate is closer to 1%
o Switzerland reports 1st death
o South Africa confirms 1st case
o UK chief medical officer confirms ‘human-to-human’ infections are happening in UK
o UK case total hits 115
o Google, Apple, Netflix cancel events
o HSBC sends research department and part of London trading floor home
o Facebook contract infected in Seattle
o Microsoft, Google, Amazon, Netflix cancel events and/or ask employees to work from home
o Netherlands cases double to 82
o Spain cases climb 40, 1 new death
o Belgium reports 27 new cases bringing total to 50
o Germany adds 87 cases bringing total to 349

Read more

SARS-CoV2/COVID-19 Update 3 March 2020

This will be a short update. Issues covered will be on COVID-19 spread, World Headlines, COVID-19 medical developments regards PPE & the role of building contamination in spreading disease in Japan, and the social media and videos COVID-19 tracking source section.
 
Top line, There are currently 92,138 confirmed COVID-19 cases worldwide, including 3,134 fatalities as of the 3 March 2020 at 5:51 a.m. ET time hack on the BNO News corona virus traking site (https://bnonews.com/index.php/2020/02/the-latest-coronavirus-cases/) There are 70(+) and growing nations including China plus three “Chinese special administrative regions” (Macao, Hong Kong and Taiwan) that have reported COVID-19 infections. China, Taiwan, Hong Kong, Japan, Thailand, Singapore, Italy, Iran, Germany, R.O.K. and the USA all appear to have local, or endemic, spread of the disease.
The reality of personal protective equipment shortages in the USA because we outsourced most such production to China.
The reality of personal protective equipment shortages in the USA because we outsourced most such production to China and many regional medical systems sent a lot of our existing medical PPE to China in January 2020 per the request of the CDC.
 
World Headline Summary (As of late evening 3/2/2020):
 
o US death toll climbs to 6; all in WA, which has 18 cases
o 2 new cases confirmed in Tampa Bay
o 1st case reported in New Hampshire
o Hubei reports 114 new cases, 31 new deaths
o Santa Clara County confirms 2 more cases, bringing county total to 9
o Gottlieb warns US cases likely in ‘low thousands’
o Illinois announces 4th case
o Boris Johnson: “A very significant expansion” of the virus is “clearly in the cards”
o Italian death toll climbs 18 to 52 while total cases surpasses 2,000
o BMW tells 150 to quarantine after Munich employee infected
o Algeria total hits 5
o Senegal becomes 2nd sub-Saharan country to confirm virus
o WHO’s Tedros: Virus is “common enemy” of humanity so don’t focus on blame
o Jordan reports first two cases
o French death toll revised to 3, total cases climb to 191
o Tunisia reports first case
o UK total climbs to 40
o OECD warns global growth could fall by half
o Indonesia reports first cases
o “Progress is being made” toward a vaccine
o Cuomo says NY expects more cases
o India confirms 2 more cases
o ‘Official’ Iran death toll hits 66
o EU confirms 38 deaths across 18 members
o First cases confirmed in Fla.
o 2 Amazon employees test positive in Milan
o Virus now in 8 US states: Washington, California, Illinois, Rhode Island, New York, Florida, Oregon and New Hampshire
o San Antonio virus patient re-hospitalized after testing positive
o China warns it could face ‘locust invasion’
 
COVID-19 MEDICAL DEVELOPMENTS
 
This article is very much worth reading in full, printing out a copy, highlighting and carrying around. I’ll excerpt a couple of sections from it below the title and link:
 
Unmasked: Experts explain necessary respiratory protection for COVID-19
by Stephanie Soucheray
CIDRAP News, Feb 13, 2020
 
 

Read more